Beilstein J. Org. Chem.2017,13, 1204–1211, doi:10.3762/bjoc.13.119
engineering strategies in the light of the newly emerging structural information on megasynthases, and argue that fatty acid synthases (FAS) are and will be valuable objects for further developing this field.
Keywords: fatty acid synthases; megasynthases; metabolicenzymeengineering; polyketide synthases
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Graphical Abstract
Figure 1:
Megasynthases – chemistry and modes of action. a) Products of PKS and FAS megasynthases. b) Reactio...